Welcome to the Bussemaker Lab at Columbia University


This site supports:

"A Gene Expression Map for the Euchromatic Genome of Drosophila melanogaster"

Stolc V, Gauhar Z, Mason C, Halasz G, van Batenburg MF, Rifkin SA, Hua S, Herreman T, Tongprasit W, Barbano PE, Bussemaker HJ, White KP

Science, Oct 22, 2004

ERRATUM: Please note an error in the published paper relating to co-regulated expression in syntenic blocks (Figures 2B-2D).


For more information on the method used to determine which probes were significantly expressed above background, please refer to the discussion in our 2006 Genome Biology paper. The analysis pipeline it describes is now implemented as TranscriptionDetector, a C program freely available for download.


For information about the array design and downloading the raw expression data, please refer to the Kevin White Lab at Yale University.


Scroll down for more information about our analysis procedure and to download results.


Click on the image below to view our data and analysis results in the context of the Drosophila genome annotation, using Gbrowse.





Probes Expressed Above Background (PEAB)

Click here for a discussion of "stringent" vs. "lenient" negative control sets, as well as other notes on our methodology.


Differentially Expressed Probes (ANOVA)

Corroboration of Gene Predictions